BioinfoAgentBench

A benchmark for bioinformatics agents, covering task completion, PARE capabilities, and scientific research.

01

Baseline

Task completion

810tasks
02

Fingerprint

PARE capabilities

100tasks
03

Frontier

Scientific problem solving

5cases
7Task sources
8PARE subdimensions
6Evaluated agents

Benchmark tiers

Baseline01

Can the agent complete the task?

A broad collection of bioinformatics tasks with explicit deliverables and verification rules.

Fingerprint02

What are its strengths and limitations?

A capability profile across Planning, Acting, Rectifying, and Evolving, grounded in calibrated task loads.

Frontier03

How far can it take a scientific question?

Research-oriented challenges connecting analytical workflows, reference findings, and numerical evidence.

PARE capabilities

Compare fingerprints
P

Planning

Decompose a scientific goal and choose appropriate methods.

A

Acting

Generate analytical results and follow the stated requirements.

R

Rectifying

Resolve ambiguous instructions and check the supplied data.

E

Evolving

Use experience and adapt strategies to a new task.

Baseline

AgentCorrectnessResource use
B1 · Success rateB2 · Subject macro-averageB3 · Token usage (k/task)B4 · Execution time (min/task)B5 · Interaction turns (/task)B6 · Cost (USD/task)B7 · Cost (USD/pass)
AutoBA0.340.3972.3834.4127.100.2470.726
BioMaster0.050.1168.9214.817.770.2675.340
Biomni0.780.76243.653.705.620.1160.148
BixBench-Agent0.760.7640.764.566.650.1280.168
STELLA0.710.74367.816.2620.230.2470.347
BioMedAgent0.730.72167.5710.3713.210.4120.565

PARE fingerprint

AgentB6 · Cost
(USD/task)
PlanningActingRectifyingEvolving
P1P2A1A2R1R2E1E2
AutoBA0.5690.1330.2150.3520.4000.4400.1250.1210.243
BioMaster0.2720.0000.0000.0280.0240.2000.0000.0000.000
Biomni0.1050.6440.7090.7890.8000.6800.7500.7070.757
BixBench-Agent0.1220.8440.8860.8870.9040.6000.7500.7590.919
STELLA0.3020.7560.7720.8030.8240.7600.1880.6210.649
BioMedAgent1.1670.8220.8990.8310.8560.8000.7500.6550.838

Frontier

AgentF1 · ApproachingF2 · ReproducingF3 · Exceeding
AutoBA0.3750.0000.000
BioMaster0.4000.0150.000
Biomni0.8000.0900.067
BixBench-Agent0.6500.1070.067
STELLA0.7250.1990.067
BioMedAgent0.8500.1990.133
Task details